Isotopically Labeled Compounds
Medchemexpress LLC Escitalopram-d6 oxalate | 1217733-09-9 | C22H17D6FN2O5 | 1 MG
Escitalopram-d6 oxalate is a deuterium-labeled form of Escitalopram oxalate, a selective serotonin reuptake inhibitor (SSRI) with high binding affinity and selectivity. It is an antidepressant used in research for major depression. Deuterium-labeled compounds are valuable as tracers and internal standards in drug development and quantitative analysis.
- Deuterium labeled compound
- Functions as a selective serotonin reuptake inhibitor (SSRI)
- Applicable as a tracer in research
- Suitable as an internal standard for quantitative analysis (NMR, GC-MS, LC-MS)
- Used for major depression research
- Contains stable heavy isotopes for drug development quantitation
Cambridge Isotope Laboratories 2 4 5-Tribromoanisole (ring-13C6 99%) 100 ug/mL in toluene 1 2 mL
2 4 5-Tribromoanisole (ring-13C6 99%) 100 ug/mL in toluene 1 2 mL
Medchemexpress LLC Benzoic-carboxy-13C acid, 2-methyl- | 70838-82-3 | 99% | 137.14 | 25 MG
o-Toluic acid-13C is the 13C labeled version of o-Toluic acid (2-Methylbenzoic acid), which is a benzoic acid substituted with a methyl group at position 2. It functions as a xenobiotic metabolite. This product is intended for research use only and is not sold to patients.
- 13C labeled o-Toluic acid.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes like 13C can affect the pharmacokinetic and metabolic profiles of drugs.
![Medchemexpress LLC L-alanine-13C2,15N | 312623-85-1 | MFCD34676307 | 99.0% | 92.07 g/mol | C[13C]2H7[15N]O2 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000296328.png-250.jpg)
Medchemexpress LLC L-alanine-13C2,15N | 312623-85-1 | MFCD34676307 | 99.0% | 92.07 g/mol | C[13C]2H7[15N]O2 | 10 MG
L-Alanine-13C2,15N is L-alanine labeled with two 13C atoms and one 15N atom, supplied as a high-purity isotopically labeled standard for use in analytical and metabolic studies.
- Isotopically labeled with two 13C and one 15N
- High purity: 99.0%
- Suitable as a tracer and internal standard for NMR, GC-MS, and LC-MS
- Molecular weight: 92.07 g/mol
- Available as a 10 MG vial for analytical use
Medchemexpress LLC Enalapril-d5 (maleate) | 349554-02-5 | 99.0% | 1 MG
Enalapril-d5 (maleate) is deuterium labeled Enalapril, an angiotensin converting enzyme (ACE) inhibitor. Intended for research use only, this compound serves as a valuable tool for quantitative analysis.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Pantothenic acid-13C3,15N hemicalcium | 356786-94-2 | 99.3% | 5 MG
Pantothenic acid-13C3,15N (hemicalcium) is the 13C-labeled and 15N-labeled D-Pantothenic acid. D-Pantothenic acid is an essential trace nutrient that functions as the obligate precursor of coenzyme A (CoA). D-Pantothenic acid plays key roles in myriad biological processes, including many that regulate carbohydrate, lipid, protein, and nucleic acid metabolism.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process.
- Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Piribedil-d8 | 1398044-45-5 | 99.8% | 1 MG
Piribedil-d8 is a deuterium-labeled analog of Piribedil, an antiparkinsonian agent known for its activity as a dopamine D2 and D3 agonist and α2-adrenoceptors antagonist. This compound serves as a valuable tracer and internal standard for quantitative analysis in various analytical techniques, including NMR, GC-MS, and LC-MS.
- Can be used as a tracer
- Functions as an internal standard for quantitative analysis
- Acts as a dopamine D2 and D3 agonist
- Serves as an α2-adrenoceptors antagonist
- Inhibits MLL1 methyltransferase activity
- Potential for research in Parkinson's disease, circulatory disorders, and cancers
Medchemexpress LLC Eravacycline-d4 (dihydrochloride) | 100.0% | 635.50 | 500 UG
Eravacycline-d4 (TP-434-d4) dihydrochloride is a deuterium labeled Eravacycline, functioning as a potent and broad-spectrum antibacterial agent. It is designed for research use and can be utilized as a tracer or an internal standard.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes are incorporated for quantitation during drug development.
- Deuteration can affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC D-Glucose-13C2-4 | 138079-87-5 | 98.0% | 25 MG
D-Glucose-13C2-4 is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. It is a carbohydrate sweetener and a critical component of general metabolism, serving as a critical signaling molecule in relation to both cellular metabolic status and biotic and abiotic stress response.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes have been incorporated into drug molecules for quantitation during drug development.
- Deuteration has potential to affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Zonisamide-d4 | 1020720-04-0 | 99.4% | 1 MG
Zonisamide-d4 is a deuterium-labeled version of Zonisamide, which is an inhibitor of the zinc enzyme carbonic anhydrase (CA). It demonstrates antiepileptic activity and is utilized in research for epilepsy, seizures, and Parkinson's disease. Deuterium labeling has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis via NMR, GC-MS, or LC-MS.
Medchemexpress LLC Docosanoic acid-d4-1 (Behenic acid-d4-1) | 1219804-98-4 | 99.0% | 344.61 | 5 MG
Docosanoic acid-d4-1 (Behenic acid-d4-1) is the deuterium-labeled Docosanoic acid. It is a long-chain saturated fatty acid that inhibits the double-stranded DNA (dsDNA) binding activity of the p53 DNA binding domain with a Kd of 12 nM. Docosanoic acid has low bioavailability and can increase cholesterol in humans.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Ivacaftor-d18 (synonyms: VX-770-d18) | 1413431-05-6 | 92.9% | 1 MG
Ivacaftor-d18 is the deuterium labeled Ivacaftor. It is a potent and orally bioavailable CFTR potentiator, targeting G551D-CFTR and F508del-CFTR with EC50s of 100 nM and 25 nM, respectively. It is intended for research use only.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Molecular weight: 410.60
- Formula: C24H10D18N2O3
- Appearance: solid
- Color: white to off-white
- Unlabeled CAS: 873054-44-5
Medchemexpress LLC S-Mirtazapine-d3 | 61337-87-9 | 99.0% | 1 MG
(S)-Mirtazapine-d3 is a deuterium labeled (S)-Mirtazapine, which is an S(+)-enantiomer of Mirtazapine. It exhibits pronociceptive properties in an animal model of acute thermal nociception and acts as a stereoselective 5-HT2 receptor antagonist. This compound is metabolized by CYP2D6 and CYP1A2.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stereoselective 5-HT2 receptor antagonist.
- Metabolized by CYP2D6 and CYP1A2.
Medchemexpress LLC Erythromycin-13C,d3 | 2378755-50-9 | 99.50% | 1 MG
Erythromycin-13C,d3 is a 13C- and deuterium labeled macrolide antibiotic. It is produced by the actinomycete *Streptomyces erythreus* and exhibits a broad spectrum of antimicrobial activity. The compound works by binding to bacterial 50S ribosomal subunits, thereby inhibiting RNA-dependent protein synthesis by blocking transpeptidation and/or translocation reactions without affecting nucleic acid synthesis.
- Used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Purity of 99.50% by HPLC
- Isotope-labeled compound
- Deuterium (2H, D) labeled
- Carbon-13 (13C) labeled
- Stable isotope-labeled inhibitor
Medchemexpress LLC Phenacetin-13C | 72156-72-0 | 99.9% | 50 MG
Phenacetin-13C is the 13C labeled Phenacetin, a non-opioid analgesic/antipyretic agent that acts as a selective COX-3 inhibitor. It is used as a probe for cytochrome P450 enzymes CYP1A2 in human liver microsomes and in rats. This compound serves as a tracer and internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
- 13C labeled compound
- Non-opioid analgesic/antipyretic agent
- Selective COX-3 inhibitor
- Probe for cytochrome P450 enzymes
- Tracer for quantitative analysis
- Internal standard for quantitative analysis